ICU sedation, delirium & recovery
Effect of Neuromuscular Electrical Stimulation in Patients With Critical Illness: An Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials
Pooled result · Occurrence of ICU-AWResult — go to the resultRelative risk 0.48 95% CI 0.32–0.72Authors' conclusion
This updated meta-analysis revealed that the use of NMES may result in a lower occurrence of ICU-AW in patients with critical illness, but its use may have little to no effect on pricking sensation in patients.
Study context
- Population
- Patients with critical illness8 new + 10 previous studies
- Comparison
- Neuromuscular electrical stimulation (NMES) vs no NMES
- Outcome
- Occurrence of ICU-acquired weakness (ICU-AW) and adverse events
Methodological detailsGRADE certainty assessment
- GRADE certainty assessment
Pooled result
Occurrence of ICU-AW
Relative risk
0.48
95% CI 0.32–0.72
NMES vs Control
RR 0.48 (95% CI 0.32–0.72)
As reported in the abstract
Further pooled results
| Outcome | Estimate | |
|---|---|---|
| Change in muscle massFour trials | MD −10.01 (95% CI −15.54 to −4.48) | |
| Muscle strengthSix trials | SMD 0.43 (95% CI 0.19–0.68) | |
| −20−10010Difference (linear scale) |
ICU LOS
- NMES may result in little to no difference in ICU LOS
Mortality and quality of life
- Evidence uncertain about the effect
Safety
| Outcome | RR (95% CI) | |
|---|---|---|
| Pricking sensation (adverse event)Eight trials · may have little to no effect | 6.87 (0.84–56.50) | |
| 0.050.21520Relative risk (log scale) |
Original publication
Effect of Neuromuscular Electrical Stimulation in Patients With Critical Illness: An Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials. Crit Care Med. Published 26 May 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →