Perioperative medicine & outcomes
Effect of a repeated verbal reminder of orientation on emergence agitation after general anaesthesia for minimally invasive abdominal surgery: a randomised controlled trial
Primary result · Emergence agitation in the operating roomResult — go to the resultRelative risk 0.5 95% CI 0.3–0.7Authors' conclusion
Repeated verbal stimulation of orientation may serve as a simple and easily applicable strategy to reduce emergence agitation after general anaesthesia.
Study context
- Population
- Patients aged 18–70 yr undergoing minimally invasive abdominal surgery under GA
- Participants
- 57 vs 57
- Comparison
- Orientation vs Control
- Orientationn = 57
- Controln = 57reference
- Primary endpoint
- Incidence of emergence agitation (Riker SAS ≥5)
Methodological detailsprospective, observer-blinded
- Prospective
- Observer-blinded
Primary result
Emergence agitation in the operating room
Relative risk
0.5
95% CI 0.3–0.7
P < 0.001
Events by treatment group
Orientation vs Control
RR 0.5 (95% CI 0.3–0.7); P < 0.001
As reported in the abstract
Secondary outcomes
Dangerous agitation (SAS=7)
P = 0.001
Median
| Outcome | Orientation | Control | P value |
|---|---|---|---|
| Maximal SAS score in the operating room | 4 (IQR 4–5) | 5 (IQR 4–6) | P < 0.001 |
Recovery profile until 24 h postoperatively (non-agitation secondary outcomes)
- Comparable between the two groups
Original publication
Effect of a repeated verbal reminder of orientation on emergence agitation after general anaesthesia for minimally invasive abdominal surgery: a randomised controlled trial. Br J Anaesth. Published 23 January 2023. doi:10.
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