Perioperative medicine & outcomes
Effect of erector spinae plane block on postoperative nausea and vomiting in lumbar disc herniation surgery
Authors' conclusion
ESP block reduced PONV incidence and severity while providing effective analgesia in LDH surgery.
Study context
- Population
- ASA I–II patients undergoing elective single-level lumbar disc herniation (LDH) surgery under GA81 analysed
- Participants
- 92 patients
- Comparison
- Bilateral erector spinae plane (ESP) block vs sham block
- Group En = 40
- Group Cn = 41reference
- Primary endpoint
- Postoperative nausea and vomiting (PONV) incidence (significant nausea Numerical Rating Scale (NRS)≥4, vomiting, or need for rescue medication)
- Follow-up
- 0-24 hours
Methodological detailsprospective, double-blind, sham-controlled
- Prospective
- Double-blind
- Sham-controlled
Primary result
As reported in the abstract
Overall PONV incidence
P < 0.05
Further findings
Nausea incidence · 0-2, 2-4, and 4-12 hours
- Significantly lower in Group E (p<0.05)
Rescue antiemetic use
- Lower in Group E (p<0.05)
Intraoperative remifentanil requirements
- Decreased in Group E (p<0.05)
Pain intensity · 0-2, 2-4, and 4-12 hours
- Significantly lower in Group E (p<0.05)
Rescue analgesic use · 0-24 hours
- Reduced in Group E (p<0.05)
Correlation of postoperative pain and nausea intensity
- Strong positive correlation at 0-2 hours (p<0.001)
- Moderate correlations at 2-4, 4-12 (p<0.001) and 12-24 hours (p=0.003)
Original publication
Effect of erector spinae plane block on postoperative nausea and vomiting in lumbar disc herniation surgery. Reg Anesth Pain Med. Published 30 June 2025. doi:10.
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