ICU sedation, delirium & recovery
Effect of inhaled anaesthetics on cognitive and psychiatric outcomes in critically ill adults: a systematic review and meta-analysis
An erratum to this article was published (Br J Anaesth, Oct 2023 ↗)
Pooled result · Delirium incidenceResult — go to the resultRelative risk 0.95 95% CI 0.59–1.54Authors' conclusion
Based on the limited evidence available, there is no difference in cognitive and psychiatric outcomes between adults exposed to volatile sedation or intravenous sedation in the ICU.
Study context
- Population
- Critically ill adults sedated in the ICU (post-cardiac arrest, postoperative noncardiac, postoperative cardiac, mixed medical-surgical)13 studies
- Comparison
- Inhaled anaesthetics vs i.v. sedatives
- Outcome
- Delirium incidence
Pooled result
As reported in the abstract
Relative risk
0.95
95% CI 0.59–1.54
Inhaled anaesthetics vs i.v. sedatives
RR 0.95 (95% CI 0.59–1.54)
Further pooled results
Hallucinations and psychomotor recovery
- Fewer hallucinations and faster psychomotor recovery with inhaled anaesthetics vs i.v. sedatives
Other cognitive and psychiatric outcomes
- No differences in other outcomes
- Heterogeneity in instruments used and timing of assessments
Original publication
Effect of inhaled anaesthetics on cognitive and psychiatric outcomes in critically ill adults: a systematic review and meta-analysis. Br J Anaesth. Published 19 June 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →