Perioperative medicine & outcomes
Effect of Pericapsular Nerve Group Block on Prehabilitation in Femoral Neck Fractures: A Randomized, Double-Blind, Placebo-Controlled Trial
Authors' conclusion
PENG block administered before the initial prehabilitation was associated with reduced movement-related pain and rescue analgesic use but did not improve the initial prehabilitation completion or postoperative functional recovery.
Study context
- Population
- Adults with Garden III to IV femoral neck fractures awaiting hip arthroplastyrandomised
- Participants
- 100 adults
- Comparison
- Pericapsular nerve group (PENG) block vs saline before initial prehabilitation
- PENGn = 50
- Placebon = 50reference
- Primary endpoint
- Completion of all five predefined mobilization steps of the prehabilitation session
Methodological detailssingle-centre, double-blind, placebo-controlled
- Single-centre
- Double-blind
- Placebo-controlled
Primary result
As reported in the abstract
Completion of all five predefined mobilization steps (full prehabilitation session)
- PENG vs Placebo: P = 0.841
- Intention-to-treat
Secondary outcomes
Rescue analgesia · within 24 hours
P = 0.028
Median
| Outcome | PENG | Placebo | P value |
|---|---|---|---|
| Maximum movement pain during prehabilitation | 7 (IQR 5–8.75) | 8 (IQR 7–10) | P = 0.022 |
Postoperative outcomes (Cumulated Ambulation Score POD 1-3, Barthel Index, LOS, discharge disposition)
- No between-group differences in postoperative outcomes
Safety
- No block-related or prehabilitation-related adverse events occurred
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Effect of Pericapsular Nerve Group Block on Prehabilitation in Femoral Neck Fractures: A Randomized, Double-Blind, Placebo-Controlled Trial. Anesth Analg. Published 15 June 2026. doi:10.
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