Perioperative medicine & outcomes
Effect of Preoperative Autologous Blood Storage in Major Hepatectomy for Perihilar Malignancy: A Randomized Controlled Trial
Authors' conclusion
Autologous blood storage did not contribute to reducing the incidence of PHLF in patients undergoing major hepatectomy.
Study context
- Population
- Patients undergoing major hepatectomy with extrahepatic bile duct resection for perihilar malignancy113 analysed (full analysis set)
- Participants
- 138 patients
- Comparison
- Surgery with vs without autologous blood transfusion
- Blood storagen = 68
- Non-storagen = 70reference
- Primary endpoint
- Incidence of clinically relevant post-hepatectomy liver failure (PHLF) (grade B/C, International Study Group of Liver Surgery definition)
Primary result
As reported in the abstract
Clinically relevant PHLF
P = 0.760
Further findings
| Outcome | P value |
|---|---|
| Clavien-Dindo grade III or higher complications72% vs 72%; no between-group difference | P = 0.997 |
| Hospital stayMedian 25 vs 29 days; no between-group difference | P = 0.277 |
Surgical procedures, operative time and blood loss
- Not significantly different between the 2 groups
Original publication
Effect of Preoperative Autologous Blood Storage in Major Hepatectomy for Perihilar Malignancy: A Randomized Controlled Trial. Ann Surg. Published 27 September 2024. doi:10.
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