Cardiac arrest & resuscitation
Effect of vascular access strategy on long-term outcomes in patients with out-of-hospital cardiac arrest: a randomised clinical trial
Primary result · SurvivalResult — go to the resultRR for survival (alive at 1 year) 1.24 95% CI 0.91–1.67Authors' conclusion
Long-term outcomes were similar between patients who received initial intraosseous versus intravenous vascular access during adult out-of-hospital cardiac arrest.
Study context
- Population
- Adults with non-traumatic OHCA in whom vascular access was indicated (IVIO trial)3 lost to 1-year follow-up
- Participants
- 1,479 adults
- Comparison
- Initial intraosseous vs intravenous vascular access
- Primary endpoint
- Survival
- Follow-up
- 1 year
Methodological detailsprespecified long-term outcomes
- Prespecified long-term outcomes
Primary result
As reported in the abstract
RR for survival (alive at 1 year)
1.24
95% CI 0.91–1.67
Events by treatment group
Intraosseous vs Intravenous
RR for survival (alive at 1 year) 1.24 (95% CI 0.91–1.67)
Further findings
| Outcome | Intraosseous | Intravenous | RR for survival with favourable neurological outcome (95% CI) | |
|---|---|---|---|---|
| Survival with favourable neurological outcome (modified Rankin Scale 0-3) · 1 year | 10% | 8% | 1.28 (0.93–1.77) | |
| 0.512RR for survival with favourable neurological outcome (log scale) |
Mean
| Outcome | Intraosseous | Intravenous | Mean difference (95% CI) | |
|---|---|---|---|---|
| EQ-5D-5L numeric score among survivors | 83 | 76 | 7 (1–13) | |
| −1001020Difference (linear scale) |
Original publication
Effect of vascular access strategy on long-term outcomes in patients with out-of-hospital cardiac arrest: a randomised clinical trial. Resuscitation. Published 10 April 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →