Obstetric anesthesia

Effect of phenylephrine rescue injection on hypotension after spinal anaesthesia for caesarean delivery when guided by both heart rate and SBP during an early warning window: A randomised controlled trial

Eur J AnaesthesiolPublished Randomised controlled trial

Authors' conclusion

After spinal anaesthesia for caesarean delivery, when phenylephrine infusion is guided by HR along with BP from a warning window it effectively reduces the incidence of hypotension without any significant effect on incidence of hypertension.

Study context

Population
Pregnant women scheduled for elective caesarean delivery under spinal anaesthesia with continuous IV phenylephrine infusion86 eligible
Participants
110 women
Comparison
Win-Group vs BP-Group
Primary endpoint
Incidence of hypotension
Methodological detailssingle-centre, Teaching hospital
  • Single-centre
  • Teaching hospital

Primary result

As reported in the abstract

Hypotension

P = 0.001

Secondary outcomes

Minimum SBP

P = 0.004

Hypertension

No significant difference between groups

Original publication

Effect of phenylephrine rescue injection on hypotension after spinal anaesthesia for caesarean delivery when guided by both heart rate and SBP during an early warning window: A randomised controlled trial. Eur J Anaesthesiol. Published 28 February 2024. doi:10.1097/eja.0000000000001977

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