Effect of transcutaneous electrical acupoint stimulation for preemptive analgesia on intraoperative opioid dosage in burn patients: a randomized, double-blind, controlled trial
Authors' conclusion
The preoperative application of TEAS for preemptive analgesia can reduce intraoperative remifentanil dosage. Meanwhile, it has a positive effect on early postoperative analgesia and gastrointestinal adverse reactions.
Study context
- Population
- Burn patients undergoing wound debridement under GA
- Participants
- 86 patients
- Comparison
- Preoperative transcutaneous electrical acupoint stimulation (TEAS) vs false stimulation
- TEASn = 43
- Controln = 43reference
- Primary endpoint
- Intraoperative remifentanil dosage
Methodological detailsdouble-blind, retrospectively registered
- Double-blind
- Retrospectively registered
Primary result
As reported in the abstract
TEAS
0.65
interval 0.45,1.00
Control
0.90
interval 0.67,1.23
P < 0.05
Secondary outcomes
| Outcome | P value |
|---|---|
| Resting F-VAS after stimulation (F2) and at 24 h after surgery (F3)Lower in the TEAS group | P < 0.05 |
| Resting F-VAS before stimulation (F1) and at 48 h after surgery (F4)No significant differences | P > 0.05 |
| Use of rescue analgesics · until POD1Comparable | P > 0.05 |
Intraoperative propofol dosage
- No significant difference between groups
Safety
| Outcome | P value |
|---|---|
| Nausea-vomiting and constipation · until POD1Lower incidence in the TEAS group | P < 0.05 |
| Drowsiness and dizziness · until POD1No significant difference | P > 0.05 |
Original publication
Effect of transcutaneous electrical acupoint stimulation for preemptive analgesia on intraoperative opioid dosage in burn patients: a randomized, double-blind, controlled trial. Perioper Med (Lond). Published 13 February 2026. doi:10.
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