Perioperative medicine & outcomes
Effectiveness of hypotension prediction index software in reducing intraoperative hypotension in prolonged prone-position spine surgery: a single-center clinical trial
Authors' conclusion
HPI-guided management did not significantly reduce the TWA of IOH compared to standard care in patients undergoing prone-position spine surgery.
Study context
- Population
- Adults undergoing spine fusion surgery in the prone position77 analysed
- Participants
- 85 adults
- Comparison
- Hypotension Prediction Index (HPI) software-guided intraoperative hypotension (IOH) management vs standard care
- Interventionn = 39
- Primary endpoint
- Time-weighted average (TWA) of IOH
Methodological detailssingle-centre, single-blind, 1:1 allocation, 8 patients excluded due to technical issues
- Single-centre
- Single-blind
- 1:1 allocation
- 8 patients excluded due to technical issues
Primary result
As reported in the abstract
TWA of IOH
P-value 0.088
Secondary outcomes
Total duration of hypotensive events per patient · significantly lower in the intervention group
p-value 0.019
Safety
Postoperative complications
- Complication rates did not differ significantly between groups
Original publication
Effectiveness of hypotension prediction index software in reducing intraoperative hypotension in prolonged prone-position spine surgery: a single-center clinical trial. J Clin Monit Comput. Published 23 May 2025. doi:10.
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