ICU sedation, delirium & recovery
Effects of a swallowing and oral-care program on resuming oral feeding and reducing pneumonia in patients following endotracheal extubation: a randomized, open-label, controlled trial
Primary result · Oral-feeding resumption by day 7Result — go to the resultAdjusted hazard ratio 2.35 95% CI 1.38–4.01Authors' conclusion
The SOC program effectively improved patients' odds that oral feeding would resume and the 30-day pneumonia incidence would decline.
Study context
- Population
- Critically ill patients extubated after prolonged (≥ 48 h) mechanical ventilationrandomized, analysed
- Participants
- 145 patients
- Comparison
- Swallowing and oral-care program vs usual care
- Swallowing and oral-care (SOC)n = 72
- Controln = 73reference
- Primary endpoint
- Oral-feeding resumption (Functional Oral Intake Scale level 6 or 7) and radiographically documented pneumonia
- Follow-up
- 7 days postextubation (feeding); 30 days postextubation (pneumonia)
Methodological detailsopen-label, independent outcome assessors, SOC group received on average 6.2 days of intervention (14.8 min daily)
- Open-label
- Independent outcome assessors
- SOC group received on average 6.2 days of intervention (14.8 min daily)
Primary result
Oral-feeding resumption by day 7
Adjusted hazard ratio
2.35
95% CI 1.38–4.01
Events by treatment group
SOC vs Control
aHR 2.35 (95% CI 1.38–4.01)
As reported in the abstract
Further findings
| Outcome | SOC | Control | aOR (95% CI) | |
|---|---|---|---|---|
| 30-day pneumonia · 30 days postextubationAdjusted for age and intubation > 6 days | 15.3% | 35.6% | 0.28 (0.12–0.65) | |
| 0.10.31310Adjusted odds ratio (log scale) |
Safety
- Adverse events — SOC
- 0 events
Adverse events
- No reported adverse events in the SOC group
Original publication
Effects of a swallowing and oral-care program on resuming oral feeding and reducing pneumonia in patients following endotracheal extubation: a randomized, open-label, controlled trial. Crit Care. Published 12 July 2023. doi:10.
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