Perioperative medicine & outcomes

Effects of caloric and nutrient content of oral fluids on gastric emptying in volunteers: a randomised crossover study

Br J AnaesthPublished Randomised crossover study

Authors' conclusion

Caloric and nutrient content significantly affected gastric emptying times. A high-calorie fruit juice (mango) exhibited delayed emptying times compared with a low-calorie fruit juice (blackcurrant).

Study context

Population
Healthy adult volunteers8 females and 8 males completed
Comparison
Oral fluids of different caloric and nutrient content: oat drink 3% fat, mango juice, oat drink 0.5% fat vs blackcurrant juice
Primary endpoint
Gastric emptying time (gastric ultrasound)

Primary result

As reported in the abstract

Gastric emptying time

Oat drink with 3% fat vs Blackcurrant juice: P = 0.007 · Mango juice vs Blackcurrant juice: P = 0.025

Further findings

OutcomeP value
Gastric content volume · 1 h after ingestionMango juice vs Blackcurrant juice · greater volumeP = 0.021
Gastric content volume · 1 h after ingestionOat drink with 3% fat vs Blackcurrant juice · greater volumeP = 0.003
AUC of gastric content volume-time profilesOat drink with 3% fat vs Mango juice · greater AUCP = 0.029
AUC of gastric content volume-time profilesOat drink with 3% fat vs Oat drink with 0.5% fat · greater AUCP = 0.004
AUC of gastric content volume-time profilesOat drink with 3% fat vs Blackcurrant juice · greater AUCP = 0.002
AUC of gastric content volume-time profilesMango juice vs Blackcurrant juice · greater AUCP = 0.019

Original publication

Effects of caloric and nutrient content of oral fluids on gastric emptying in volunteers: a randomised crossover study. Br J Anaesth. Published 25 November 2023. doi:10.1016/j.bja.2023.10.030

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