Paediatric anaesthesia & critical care
Effects of Intraoperative Nociception Monitoring during Adolescent Idiopathic Scoliosis Correction
Primary result · Postoperative morphine consumptionResult — go to the resultMedian difference −0.005 mg · kg −1 95% CI −0.10 to 0.09Authors' conclusion
The administration of remifentanil guided by intraoperative nociception monitoring during adolescent idiopathic scoliosis did not result in a reduction of postoperative opioid consumption.
Study context
- Population
- Children undergoing surgery for adolescent idiopathic scoliosisrandomized
- Participants
- 244 children
- Comparison
- Analgesia Nociception Index (ANI) vs Control
- ANIn = 120
- Controln = 123reference
- Primary endpoint
- Postoperative morphine consumption
- Follow-up
- Day 1
Methodological detailsmulticentre, Conducted October 2020 to June 2023
- Multicentre
- Conducted October 2020 to June 2023
Primary result
As reported in the abstract
Median difference
−0.005 mg · kg −1
95% CI −0.10 to 0.09
P = 0.93
By group
ANI
0.4
median · IQR 0.3–0.8
Control
0.4
median · IQR 0.3–0.5
ANI vs Control
median difference −0.005 mg · kg −1 (95% CI −0.10 to 0.09); P = 0.93
Secondary outcomes
| Outcome | Mean difference (μg ·kg −1) (95% CI) | P value | |
|---|---|---|---|
| Intraoperative remifentanil administrationDecreased in the ANI group | 9.5 (4–15) | P < 0.001 | |
| −1001020Difference, μg ·kg −1 (linear scale) |
Secondary outcomes (incl. persistent postoperative pain at 6 months)
- No differences between groups
Original publication
Effects of Intraoperative Nociception Monitoring during Adolescent Idiopathic Scoliosis Correction. Anesthesiology. Published 16 September 2026. doi:10.
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