Pediatric anesthesia & critical care
Intravenous lidocaine infusion therapy and intraoperative neurophysiological monitoring in adolescents undergoing idiopathic scoliosis correction: A retrospective study
Authors' conclusion
Data from these two cohorts provide preliminary evidence that intravenous lidocaine infusion has no negative impact on intraoperative neurophysiological monitoring during PSIF for adolescent idiopathic scoliosis.
Study context
- Population
- Adolescents undergoing posterior spinal instrumentation and fusion for adolescent idiopathic scoliosis with intraoperative neurophysiological monitoringsurgery 2016–2021
- Participants
- 81 adolescents
- Exposure
- IV lidocaine infusion vs no lidocaine infusion
- Lidocainen = 39
- No lidocainen = 42reference
- Outcome
- Impact on intraoperative neurophysiological monitoring (MEP amplitude; SSEP amplitude and latency), change from baseline
Main finding
As reported in the abstract
Change from baseline in MEP amplitude (hourly snapshot data)
Lidocaine vs No lidocaineMD (95% CI)P value
Lower limbs
41.9(−304.5 to 388.3)
P = 0.182Upper limbs
−279.0(−562.5 to 4.4)
P = 0.054Observational data: associations, not effects.
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Intravenous lidocaine infusion therapy and intraoperative neurophysiological monitoring in adolescents undergoing idiopathic scoliosis correction: A retrospective study. Paediatr Anaesth. Published 5 October 2024. doi:10.
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