Pediatric anesthesia & critical care
Perioperative Intravenous Lidocaine Infusion Therapy as an Adjunct to Multimodal Analgesia for Adolescent Idiopathic Scoliosis Surgical Correction: A Double‐Blind Randomized Controlled Trial
Primary result · 48-h morphine utilizationResult — go to the resultMedian difference −0.11 mg kg-1 95% CI −0.30 to 0.13Authors' conclusion
We found no evidence to support the adjunctive use of 48-h perioperative intravenous lidocaine therapy in adolescents undergoing scoliosis correction in which effective multimodal analgesia was adopted.
Study context
- Population
- 10–19 years old, ASA I–III, undergoing single-stage adolescent idiopathic scoliosis correctiondata available
- Participants
- 38 participants
- Comparison
- Intervention vs Control
- Primary endpoint
- Morphine utilization
- Follow-up
- 48 h
Methodological detailsdouble-blinded
- Double-blinded
Primary result
48-h morphine utilization
Median difference
−0.11 mg kg-1
95% CI −0.30 to 0.13
P = 0.264
By group
Intervention vs Control
median difference −0.11 mg kg-1 (95% CI −0.30 to 0.13); P = 0.264
As reported in the abstract
Secondary outcomes
| Outcome | Intervention | Control | Median difference (95% CI) | P value |
|---|---|---|---|---|
| First postoperative pain score | 3/10 (IQR 1.75–5) | 5/10 (IQR 3–7) | −2 (0 to −3) | P = 0.035 |
Morphine utilization at 12, 24, 36 h and other secondary outcomes
- No differences
Safety
- Suspected local anesthetic systemic toxicity, mild symptoms — Intervention
- 3 events
Original publication
Perioperative Intravenous Lidocaine Infusion Therapy as an Adjunct to Multimodal Analgesia for Adolescent Idiopathic Scoliosis Surgical Correction: A Double‐Blind Randomized Controlled Trial. Paediatr Anaesth. Published 6 May 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →