ICU sedation, delirium & recovery
Effects of morning versus afternoon surgery on peri‐operative disturbance of sleep–wake timing: An observational study
Authors' conclusion
Our results suggest that the timing of surgery between 08:00 h and 17:00 h does not modulate the effect of anaesthesia and surgery on phase of the sleep-wake rhythm in patients undergoing elective surgery with a low pre-operative risk of delirium.
Study context
- Population
- Adults (≥18 years) undergoing elective surgery
- Participants
- 259 adults
- Exposure
- Morning vs afternoon surgery
- Morningn = 144reference
- Afternoonn = 115
- Outcome
- Post-operative midpoint of sleep shift between morning and afternoon surgery (daily sleeping log)
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Midpoint of sleep shift, night after surgery vs 3 nights before · night after surgery
| Group | Value | p |
|---|---|---|
| Morning | mean - 00:41 (95% CI −00:27 h to −00:54 h) h | p < .001 |
| Afternoon | mean - 00:28 (95% CI −00:09 h to −00:46 h) h | p = .003 |
Value
Morningmean - 00:41 (95% CI −00:27 h to −00:54 h) h
Afternoonmean - 00:28 (95% CI −00:09 h to −00:46 h) h
p
Morningp < .001
Afternoonp = .003
- No between-group difference in midpoint of sleep shift (mean - 00:13 h, 95% CI −00:35 h-00:09 h)
- P = 0.25
Observational data: associations, not effects.
Secondary outcomes
Reduction of sleep quality
- Similar in the two groups
Factors affecting phase advance
- Larger phase advance with evening chronotype or lower pre-operative sleep quality
Factors affecting decline of sleep quality after surgery
- Larger decline with evening chronotype, longer procedures or better pre-operative sleep quality
Original publication
Effects of morning versus afternoon surgery on peri‐operative disturbance of sleep–wake timing: An observational study. Acta Anaesthesiol Scand. Published 17 November 2024. doi:10. 1111/ aas. 14543
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