Perioperative medicine & outcomes
Efficacy of a pre‐operative anaemia clinic in patients undergoing elective abdominal cancer surgery
Authors' conclusion
In patients scheduled for abdominal cancer surgery, including in patients with concomitant chemotherapy, pre-operative IDA management is feasible and results in a significant pre-operative Hb increase compared to patients not treated.
Study context
- Population
- Patients scheduled for elective abdominal cancer surgery with iron deficiency anaemia (WHO criteria; transferrin saturation <0.20)134 (75%) received IV iron
- Participants
- 178 patients
- Exposure
- Pre-operative IV iron vs no pre-operative treatment
- Treated pre-operativelyn = 103
- Not treated pre-operativelyn = 75reference
- Outcome
- Change in Hb between iron infusion and surgery in patients receiving pre-operative IV iron
Methodological details31 (17%) received post-operative IV iron
- 31 (17%) received post-operative IV iron
Main finding
As reported in the abstract
Pre-operative IV iron
0.89
95% CI 0.64–1.13 · g/dL
Not treated pre-operatively
0.4
95% CI 0.19–0.58 · g/dL
Observational data: associations, not effects.
Further findings
Pre-operative haemoglobin (Hb) increase by anaemia severity (subgroup)
- Largest pre-operative Hb increase in patients with severe anaemia
Pre-operative Hb increase among patients receiving chemotherapy ≤31 days before surgery (subgroup)
- Hb increase, 95% CI 0.19-1.21
- 0.64 g/dL
Hb increment by timing of iron infusion (subgroup)
g/dL
- Iron infusion >2 weeks pre-operatively, 95% CI 0.81-1.45
- 1.13
- Iron infusion ≤2 weeks before surgery, 95% CI 0.16-0.81
- 0.48
No longer anaemic on the day of surgery, among patients treated pre-operatively
- Patients treated pre-operatively who were no longer anaemic
- 25%
Original publication
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