Cardiac arrest & resuscitation
Efficacy of emergency department calcium administration in cardiac arrest: A 9-year retrospective evaluation
Main finding · Survival to hospital admissionResult — go to the resultRelative risk 0.74 95% CI 0.66–0.82Authors' conclusion
Calcium administration as part of ED-directed treatment for cardiac arrest was associated with lower survival to hospital admission.
Study context
- Population
- Adults (≥18 years) treated for cardiac arrest in the emergency department (ED), two academic hospitals in San Francisco, 2011–2019
- Participants
- 781 adults
- Exposure
- Calcium administration vs no calcium in the ED
- Outcome
- Survival to hospital admission
Methodological detailstwo academic hospitals, multivariable log-binomial regression, propensity score models
- Two academic hospitals
- Multivariable log-binomial regression
- Propensity score models
Main finding
As reported in the abstract
Relative risk
0.74
95% CI 0.66–0.82
Calcium vs No calcium
RR 0.74 (95% CI 0.66–0.82)
Observational data: associations, not effects.
Further findings
| Outcome | RR (95% CI) | |
|---|---|---|
| Survival to hospital admission, adjusted (age, sex, witnessed arrest), by rhythmCalcium vs No calcium · shockable rhythms | 0.60 (0.50–0.72) | |
| Survival to hospital admission, adjusted (age, sex, witnessed arrest), by rhythmCalcium vs No calcium · non-shockable rhythms | 0.87 (0.76–0.99) | |
| Survival to hospital admission, propensity score modelsCalcium vs No calcium · nearest neighbor propensity matching | 0.79 (0.68–0.89) | |
| Survival to hospital admission, propensity score modelsCalcium vs No calcium · inverse propensity weighted regression adjustment | 0.75 (0.67–0.84) | |
| 0.512Relative risk (log scale) |
Original publication
Efficacy of emergency department calcium administration in cardiac arrest: A 9-year retrospective evaluation. Resuscitation. Published 9 August 2023. doi:10. 1016/ j. resuscitation. 2023. 109933
Composed by AI from the published abstract and checked against it. How Briefs are made →