Hemodynamics, fluids & transfusion
Endotypes of intraoperative hypotension during major abdominal surgery: a retrospective machine learning analysis of an observational cohort study
Authors' conclusion
Hierarchical clustering identified six endotypes of intraoperative hypotension.
Study context
- Population
- Patients having major abdominal surgery under GA82 with hypotension
- Participants
- 100 patients
- Primary endpoint
- Endotypes of intraoperative hypotension (MAP ≤65 mm Hg, or 66–75 mm Hg requiring norepinephrine >0.1 μg kg-1 min-1) identified by hierarchical clustering
Methodological detailsretrospective, machine learning, hierarchical clustering (Ward's method)
- Retrospective
- Machine learning
- Hierarchical clustering (Ward's method)
Primary result
As reported in the abstract
Intraoperative hypotension endotypes
Episodes of intraoperative hypotension
615
Distinct endotypes identified
6
Original publication
Endotypes of intraoperative hypotension during major abdominal surgery: a retrospective machine learning analysis of an observational cohort study. Br J Anaesth. Published 6 December 2022. doi:10.
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