Perioperative medicine & outcomes

Enhanced Recovery Protocols Reduce Mortality Across Eight Surgical Specialties at Academic and University-affiliated Community Hospitals

Ann SurgPublished Retrospective case-control study

Authors' conclusion

ERPs improve short and long-term mortality, clinical outcomes, length of stay, and discharge disposition to home.

Study context

Population
Adults undergoing nonemergent, major orthopedic or abdominal surgery (hip/knee replacement, hepatobiliary, colorectal, gynecology oncology, bariatric, general, urological) in 5 academic and community hospitals within a single health system3,367 ERP patients matched
Participants
9,492 adults
Comparison
Simplified ERP vs pre-implementation control
  • ERPn = 5,185
  • Controln = 4,307reference
Outcome
Short and long-term mortality
Follow-up
30 day, 1-year, 2-year
Methodological detailspropensity-matched, multicentre, before-after implementation
  • Propensity-matched
  • Multicentre
  • Before-after implementation

Main finding

As reported in the abstract

Mortality
  • 30-day mortality: ERP 0.2% vs control 0.6% (P = 0.002)
  • 1-year mortality: ERP 3.9% vs control 5.1% (P < 0.0001)
  • 2-year mortality: ERP 6.2% vs control 9.0% (P < 0.0001)
  • Propensity-matched

Observational data: associations, not effects.

Further findings

LOS

P < 0.0001

Discharge to a facility

P < 0.0001

30-day readmission

No significant difference

Safety

OutcomeP value
ComplicationsP < 0.02

Complications

All complications except VTE significantly reduced in ERP

Original publication

Enhanced Recovery Protocols Reduce Mortality Across Eight Surgical Specialties at Academic and University-affiliated Community Hospitals. Ann Surg. Published 18 November 2020. doi:10.1097/sla.0000000000004642

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