Safety, quality & education

Epidemiological, methodological, and statistical characteristics of network meta-analysis in anaesthesia: a systematic review

Br J AnaesthPublished Systematic review

Authors' conclusion

Anaesthesia NMAs need improvement in their conduct and reporting.

Study context

Population
Network meta-analyses (NMAs) in anaesthesia
Participants
62 included NMAs
Outcome
Compliance with 29 binary checklist items (very low ≤25%, low 26-50%, fair 51-75%, high >75%)
Methodological detailsmethodological review of network meta-analyses, 64-item checklist, post hoc comparison with cancer and Cochrane NMAs
  • Methodological review of network meta-analyses
  • 64-item checklist
  • Post hoc comparison with cancer and Cochrane NMAs

Pooled result

As reported in the abstract

Checklist compliance
  • Low compliance (26-50%): protocol registration, use of PRISMA-NMA, publication bias assessment, evidence appraisal, reporting of Bayesian methodology, consistency evaluation
  • Very low compliance (≤25%): bias assessment, biostatistician involvement, search specialist, use of predefined important differences

Original publication

Epidemiological, methodological, and statistical characteristics of network meta-analysis in anaesthesia: a systematic review. Br J Anaesth. Published 18 November 2022. doi:10.1016/j.bja.2022.08.042

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