Safety, quality & education

Methodological and reporting quality assessment of network meta-analyses in anesthesiology: a systematic review and meta-epidemiological study

Can J AnaesthPublished Systematic review and meta-epidemiological study

Authors' conclusion

The current study highlights numerous methodological and reporting deficiencies in anesthesiology NMAs.

Study context

Population
Anesthesiology network meta-analyses (NMAs) published from inception to October 2020
Participants
62 NMAs
Outcome
Methodological (AMSTAR-2) and reporting (PRISMA-NMA, PRISMA) quality of NMAs

Pooled result

As reported in the abstract

Methodological and reporting quality

NMAs rated "critically low" by AMSTAR-2 rating method

84%

52/62

AMSTAR-2 score, median [IQR]

55 [44-69]%

PRISMA score, median [IQR]

70 [61-81]%

Correlation of methodological and reporting scores

R = 0.78

Further pooled results

Factors associated with AMSTAR-2 and PRISMA scores

Higher scores if published in higher impact factor journals (AMSTAR-2; PRISMA)
P = 0.006; P = 0.01
Higher scores if PRISMA-NMA reporting guidelines followed (AMSTAR-2; PRISMA)
P = 0.001; P = 0.002
Lower scores for NMAs from China (AMSTAR-2; PRISMA)
P < 0.001; P < 0.001
Neither score improved over time (AMSTAR-2; PRISMA)
P = 0.69; P = 0.67

Original publication

Methodological and reporting quality assessment of network meta-analyses in anesthesiology: a systematic review and meta-epidemiological study. Can J Anaesth. Published 8 July 2023. doi:10.1007/s12630-023-02510-6

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