Epidemiology of sepsis-associated acute kidney injury in critically ill patients: a multicenter, prospective, observational cohort study in South Korea
Authors' conclusion
Of the patients admitted to the intensive care unit for sepsis, 62.3% developed SA-AKI. Severe SA-AKI was associated with an increased risk of mortality.
Study context
- Population
- Adults aged ≥ 19 years admitted to ICUs with sepsis, South Korea, September 2019–December 2022
- Participants
- 5,100 adults
- Comparison
- Stage 1 vs Stage 2 vs Stage 3
- Stage 1n = 613
- Stage 2n = 721
- Stage 3n = 1,843
- Primary endpoint
- Incidence of SA-AKI (Acute Disease Quality Initiative 28 Workgroup consensus definition)
Primary result
As reported in the abstract
Incidence of SA-AKI
Secondary outcomes
In-hospital mortality in severe sepsis-associated acute kidney injury (SA-AKI): adherence to fluid resuscitation component of 1-hour sepsis bundle
| aOR (95% CI) | P value | ||
|---|---|---|---|
| Adherence to fluid resuscitation component | 0.62 (0.48–0.79) | P < 0.001 | |
| 0.512Adjusted odds ratio (log scale) |
In-hospital mortality, severe SA-AKI (stages 2 and 3)
- Severe SA-AKI associated with increased risk of in-hospital mortality
Original publication
Epidemiology of sepsis-associated acute kidney injury in critically ill patients: a multicenter, prospective, observational cohort study in South Korea. Crit Care. Published 24 November 2024. doi:10.
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