Pediatric anesthesia & critical care
Epidemiology, outcomes, and factors associated with mortality in pediatric acute respiratory distress syndrome in hospitalized Thai children: a nationwide retrospective analysis, 2015–2022
Authors' conclusion
PARDS remains a substantial burden in Thailand, with marked regional differences in access to critical care.
Study context
- Population
- Children aged 1 month to < 18 years with pediatric acute respiratory distress syndrome (PARDS) (ICD-10-TM J80), Thailand National Health Security Office (NHSO) data, 2015–2022
- Participants
- 4,241 children
- Outcome
- Factors associated with mortality
Methodological detailsnationwide, multivariable logistic regression
- Nationwide
- Multivariable logistic regression
Main finding
As reported in the abstract
Adjusted relative risk (95% CI)P value
Malignancy
1.29(1.17–1.43)
P < 0.001Drowning
1.43(1.29–1.60)
P < 0.001Sepsis and septic shock
1.19(1.12–1.27)
P < 0.001Non-major pulmonary trauma
1.43(1.16–1.77)
P = 0.001Cardiovascular dysfunction
1.41(1.32–1.51)
P < 0.001Intubationincreased mortality
2.52(2.12–3.00)
P < 0.001Extracorporeal life supportlower mortality
0.46(0.35–0.61)
P < 0.001Observational data: associations, not effects.
Further findings
PARDS prevalence and PICU admission rates · 2015–2022
- PARDS prevalence per 100,000 hospital admissions
- 29.8 to 37.2
- PICU admission rate per 1,000
- 13.5 to 18.6
- Bangkok PICU admission rate in 2022 (highest), per 1,000
- 27.0
- Bangkok mortality (lowest)
- 25.6%
Overall mortality
- Mortality in 2015
- 53.7%
- Mortality in 2022
- 37.7%
- Remained high in resource-limited regions
Original publication
Epidemiology, outcomes, and factors associated with mortality in pediatric acute respiratory distress syndrome in hospitalized Thai children: a nationwide retrospective analysis, 2015–2022. Crit Care. Published 11 July 2025. doi:10.
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