ICU sedation, delirium & recovery
Estimated prevalence of post-intensive care cognitive impairment at short-term and long-term follow-ups: a proportional meta-analysis of observational studies
Authors' conclusion
The prevalence rates of post-intensive care cognitive impairment differed at different follow-up timepoints. The rates were highest within the first three months of follow-up, with a pooled prevalence of 49.8% at less than one month, 45.1% at one to three months, and 47.9% at three to six months.
Study context
- Population
- Critically ill survivors discharged from ICUs
- Participants
- 347,940 survivors · 58 studies
- Outcome
- Pooled estimated prevalence of post-intensive care cognitive impairment
- Follow-up
- < 1 month, 1 to 3 month(s), 4 to 6 months, 7-12 months, and > 12 months
Methodological detailsrandom-effects model, Newcastle-Ottawa Scale risk of bias
- Random-effects model
- Newcastle-Ottawa Scale risk of bias
Pooled result
As reported in the abstract
Pooled prevalence of post-intensive care cognitive impairment by follow-up time
- < 1 month (95% Prediction Interval (PI) 39.9%-59.7%, n = 19)
- 49.8%
- 1-3 month(s) (95% PI 34.8%-55.5%, n = 23)
- 45.1%
- 4-6 months (95% PI 35.9%-60.0%, n = 16)
- 47.9%
- 7-12 months (95% PI 19.9%-37.6%, n = 19)
- 28.3%
- > 12 months (95% PI 18.4%-43.9%, n = 7)
- 30.4%
Further pooled results
Prevalence by continent and study design (subgroup)
- Significant differences in prevalence between continents and study designs
Original publication
Estimated prevalence of post-intensive care cognitive impairment at short-term and long-term follow-ups: a proportional meta-analysis of observational studies. Ann Intensive Care. Published 10 January 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →