Estimating Sepsis Incidence Using Administrative Data and Clinical Medical Record Review
Authors' conclusion
In this cohort study of sepsis epidemiology, sepsis was a considerable burden to public health in Sweden.
Study context
- Population
- Hospitalizations in all acute care hospitals of the Scania region, Sweden, 2019 and 2020medical records reviewed
- Participants
- 997 hospitalizations
- Outcome
- Hospital and population incidences of sepsis
Methodological detailsobservational, population-based, stratified medical record review
- Observational
- Population-based
- Stratified medical record review
Main finding
As reported in the abstract
2019
Sepsis and Septic Shock (Sepsis-3) incidence in hospitalized patients (medical record review)
4.1%
95% CI 3.6–4.5
Annual incidence rate of sepsis per 100 000 population
747
95% CI 663–832
Observational data: associations, not effects.
Further findings
Patients with clinical sepsis
- Sepsis by clinical criteria among reviewed records
- 457
- Female
- 232 (51%)
- At least 1 comorbidity
- 357 (78%)
- Median (IQR) age, years
- 76 (67-85)
Temporal dynamics due to COVID-19
- No significant increase in sepsis during the COVID-19 pandemic nor a decrease when excluding COVID-19 sepsis
Antimicrobial resistance
- Few sepsis cases caused by pathogens with antimicrobial resistance
Validity of ICD-10-based case identification vs medical record review
- Validity in administrative data was low
Original publication
Estimating Sepsis Incidence Using Administrative Data and Clinical Medical Record Review. JAMA Netw Open. Published 1 August 2023. doi:10.
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