Perioperative medicine & outcomes
Estimating the effect of frailty on longer‐term survival following emergency laparotomy: an observational study using National Emergency Laparotomy Audit data*
Authors' conclusion
For older people living with frailty, increased risk of death persists further than the immediate postoperative period.
Study context
- Population
- Patients undergoing emergency laparotomy, National Emergency Laparotomy Audit (UK)
- Exposure
- Clinical Frailty Scale (CFS) 4–9 vs CFS 1-3
- Outcome
- Short- (≤ 90 days) and longer-term (> 90 days) mortality
Methodological detailsprospectively collected national audit data, linked mortality data
- Prospectively collected national audit data
- Linked mortality data
Main finding
As reported in the abstract
Death from 90 days post-surgery · > 90 days
Each group vs CFS 1-3AHR for death (95% CI)
CFS 4
1.52(1.41–1.64)
CFS 5
1.69(1.57–1.82)
CFS 6
2.14(1.98–2.31)
CFS 7
2.97(2.59–3.41)
CFS 8
4.24(3.19–5.64)
CFS 9
3.34(2.17–5.14)
Observational data: associations, not effects.
Further findings
Death in the first 90 days after surgery
- Frailty strongly associated with hazard of death
Original publication
Estimating the effect of frailty on longer‐term survival following emergency laparotomy: an observational study using National Emergency Laparotomy Audit data*. Anaesthesia. Published 27 May 2025. doi:10. 1111/ anae. 16644
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