Cardiothoracic & vascular anesthesia
Evaluating the efficacy of a continuous comprehensive nursing system on postoperative hemoglobin levels and quality of life in coronary artery bypass surgery: a randomized controlled trial
Authors' conclusion
Implementing a continuous comprehensive nursing system after CABG significantly benefits postoperative recovery, leading to improved hemoglobin levels, favorable red blood cell indices, measurable changes in immune markers, enhanced quality of life, improved mental health outcomes, and greater patient satisfaction compared to routine care.
Study context
- Population
- Patients undergoing coronary artery bypass grafting (CABG)
- Participants
- 120 patients
- Comparison
- Continuous comprehensive nursing system vs routine care after CABG
- Continuous comprehensive nursing (CCN)n = 60
- Controln = 60reference
- Primary endpoint
- Postoperative Hb levels and QoL
Methodological details1:1 allocation, computer-generated random numbers
- 1:1 allocation
- Computer-generated random numbers
Primary result
As reported in the abstract
Hb · day 7 post-surgery
P < 0.001
- Superior quality of life (QoL) scores across all WHOQOL domains (psychological, social, environmental, physical) in CCN
- all P < 0.001
Further findings
Red blood cell morphology
- Lower MCV in CCN
- P < 0.001
- Lower RDW in CCN
- P < 0.001
- Higher HCT in CCN
- P < 0.001
Immune markers (IL-2, IL-6)
- Higher IL-2 in CCN
- P < 0.001
- Lower IL-6 in CCN
- P < 0.001
Depressive and anxiety symptoms
- Reduced depressive symptoms (CES-D) in CCN
- P < 0.001
- Reduced anxiety symptoms (SAS) in CCN
- P < 0.001
Patient satisfaction
- Significantly higher patient satisfaction in CCN
- P < 0.001
Original publication
Evaluating the efficacy of a continuous comprehensive nursing system on postoperative hemoglobin levels and quality of life in coronary artery bypass surgery: a randomized controlled trial. Perioper Med (Lond). Published 26 November 2025. doi:10.
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