Hemodynamics, fluids & transfusion
Evaluation of fluid responsiveness with dynamic superior vena cava collapsibility index in mechanically ventilated patients
Authors' conclusion
The SVC-CI and SVV can predict fluid responsiveness effectively in mechanically ventilated patients. And SVC-CI is superior in predicting fluid responsiveness compared with SVV. The E/e' ratio and CVP cannot predict FR effectively.
Study context
- Population
- Mechanically ventilated patients undergoing elective general surgery, fluid challenge 10 ml/kg Ringer's lactate; responders = CI increase ≥15%52 analysed
- Participants
- 60 participants
- Comparison
- Superior vena cava collapsibility index (SVC-CI) vs stroke volume variation (SVV)
- Outcome
- Predictive accuracy for fluid responsiveness (CI increase ≥15% after fluid challenge)
Methodological detailsprospective
- Prospective
Performance
As reported in the abstract
Prediction of fluid responsiveness
| Test or model | AUC | Optimal cutoff | Sensitivity | Specificity |
|---|---|---|---|---|
| SVC-CI | 0.838 (95% CI 0.728 ≈0.947, P < 0.01) | 39.4% | 64% | 92.6% |
| SVV | 0.68 (95% CI 0.53 ≈0.826, P < 0.05) | 12.5% | 40% | 89% |
AUC
SVC-CI0.838 (95% CI 0.728 ≈0.947, P < 0.01)
SVV0.68 (95% CI 0.53 ≈0.826, P < 0.05)
Optimal cutoff
SVC-CI39.4%
SVV12.5%
Sensitivity
SVC-CI64%
SVV40%
Specificity
SVC-CI92.6%
SVV89%
Further findings
SVC-CI by fluid responsiveness
- SVC-CI higher in responders vs non-responders (%)
- 41.90 ± 11.48 vs 28.92 ± 9.05%
- P
- P < 0.01
Correlation of SVC-CI with △CI FloTrac
- R
- 0.568
- P
- P < 0.01
E/e' ratio
- No significant difference between the two groups
- P > 0.05
Original publication
Evaluation of fluid responsiveness with dynamic superior vena cava collapsibility index in mechanically ventilated patients. Perioper Med (Lond). Published 10 April 2023. doi:10.
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