Pediatric anesthesia & critical care
Evaluation of lung homogeneity in neonates and small infants during general anaesthesia using electrical impedance tomography: a prospective observational study
Authors' conclusion
General anaesthesia creates heterogenous patterns of ventilation similar to those reported during prolonged mechanical ventilation.
Study context
- Population
- Healthy neonates and infants (3 days to 12 months) without known lung disease receiving GA with endotracheal intubation for supine surgery
- Participants
- 20 neonates
- Outcome
- Regional pattern of lung ventilation (gravity-dependent and right-left centre of ventilation, CoV) by electrical impedance tomography
- Follow-up
- Six time points from induction to post-extubation
Methodological detailsAnaesthesia and ventilation management at the discretion of the treating clinician
- Anaesthesia and ventilation management at the discretion of the treating clinician
Main finding
As reported in the abstract
Gravity-dependent centre of ventilation (CoV)
Centre of ventilation (CoV) at induction (dorsal regions favoured), median (IQR)
58.2 (53.9-59.3)%
CoV early in surgery after intubation (redistribution to ventral lung, greatest change), median (IQR)
53.8 (52.3-55.2)%
CoV after extubation (returned to pre-intubation values), median (IQR)
56.5 (54.7-58)%
Observational data: associations, not effects.
Original publication
Evaluation of lung homogeneity in neonates and small infants during general anaesthesia using electrical impedance tomography: a prospective observational study. BJA Open. Published 21 September 2024. doi:10.
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