Cardiothoracic & vascular anesthesia

Evaluation of postoperative delirium in cardiac surgery patients with the SDACS screening tool: a multicenter-multiphase study

Perioper Med (Lond)Published Multiphase prediction model development study

Authors' conclusion

Chronic opioid use, hearing impairment, benzodiazepine history, and poor sleep quality post-surgery are linked to postoperative delirium in cardiac surgery patients. The SDACS screening tool effectively forecasts this syndrome early

Study context

Population
Cardiac surgery patients at three academic institutions, 2020–2023
Participants
920 patients · 3 centres
Outcome
Postoperative delirium after the first day (SDACS screening tool)
Methodological detailsmulticentre, scoping review, Delphi rounds, cross-validated, Multiphase design: scoping review of 38 papers identified 136 potential risk factors; three Delphi rounds of expert panels; 76 potential risk factors examined in 920 cardiac surgery patients at three academic institutions, 2020–2023, Regression coefficient of each predictor transformed into a risk score
  • Multicentre
  • Scoping review
  • Delphi rounds
  • Cross-validated
  • Multiphase design: scoping review of 38 papers identified 136 potential risk factors; three Delphi rounds of expert panels; 76 potential risk factors examined in 920 cardiac surgery patients at three academic institutions, 2020–2023
  • Regression coefficient of each predictor transformed into a risk score

Main finding

As reported in the abstract

Independent predictors of delirium and SDACS performance
Delirium incidence
53% (n = 488)
Chronic opioid use, OR
4.605 (95% CI 2.163-9.804)
Hearing impairment, OR
6.926 (95% CI 3.630-12.215)
Benzodiazepine history, OR
8.506 (95% CI 5.651-11.805)
Poor sleep quality on the first night after cardiac surgery, OR
9.081 (95% CI 6.225-12.248)
Cross-validated AUC of SDACS
0.897 (95% CI 0.876-0.916; P < 0.001)

Original publication

Evaluation of postoperative delirium in cardiac surgery patients with the SDACS screening tool: a multicenter-multiphase study. Perioper Med (Lond). Published 27 March 2025. doi:10.1186/s13741-025-00518-8

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