Cardiothoracic & vascular anesthesia
Evaluation of postoperative delirium in cardiac surgery patients with the SDACS screening tool: a multicenter-multiphase study
Authors' conclusion
Chronic opioid use, hearing impairment, benzodiazepine history, and poor sleep quality post-surgery are linked to postoperative delirium in cardiac surgery patients. The SDACS screening tool effectively forecasts this syndrome early
Study context
- Population
- Cardiac surgery patients at three academic institutions, 2020–2023
- Participants
- 920 patients · 3 centres
- Outcome
- Postoperative delirium after the first day (SDACS screening tool)
Methodological detailsmulticentre, scoping review, Delphi rounds, cross-validated, Multiphase design: scoping review of 38 papers identified 136 potential risk factors; three Delphi rounds of expert panels; 76 potential risk factors examined in 920 cardiac surgery patients at three academic institutions, 2020–2023, Regression coefficient of each predictor transformed into a risk score
- Multicentre
- Scoping review
- Delphi rounds
- Cross-validated
- Multiphase design: scoping review of 38 papers identified 136 potential risk factors; three Delphi rounds of expert panels; 76 potential risk factors examined in 920 cardiac surgery patients at three academic institutions, 2020–2023
- Regression coefficient of each predictor transformed into a risk score
Main finding
As reported in the abstract
Independent predictors of delirium and SDACS performance
- Delirium incidence
- 53% (n = 488)
- Chronic opioid use, OR
- 4.605 (95% CI 2.163-9.804)
- Hearing impairment, OR
- 6.926 (95% CI 3.630-12.215)
- Benzodiazepine history, OR
- 8.506 (95% CI 5.651-11.805)
- Poor sleep quality on the first night after cardiac surgery, OR
- 9.081 (95% CI 6.225-12.248)
- Cross-validated AUC of SDACS
- 0.897 (95% CI 0.876-0.916; P < 0.001)
Original publication
Evaluation of postoperative delirium in cardiac surgery patients with the SDACS screening tool: a multicenter-multiphase study. Perioper Med (Lond). Published 27 March 2025. doi:10. 1186/ s13741-025-00518-8
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