ICU sedation, delirium & recovery
Evaluation of the Impact of ABCDEF Bundle Compliance Rates on Postintensive Care Syndrome: A Secondary Analysis Study*
Authors' conclusion
The bundle compliance rate was not associated with PICS prevalence. However, 6-month mortality was lower with a higher bundle compliance rate. A trend toward a lower PICS prevalence was associated with higher bundle compliance in high-volume centers.
Study context
- Population
- Adult ICU patients expected to be on a ventilator for at least 48 hours, 14 centers and 16 ICUs in Japan, April–September 201996 with 6-month outcome data
- Participants
- 191 patients
- Comparison
- Bundle compliance rate in patients with vs without postintensive care syndrome (PICS)
- PICSn = 61
- non-PICSn = 35reference
- Primary endpoint
- Association between ABCDEF bundle compliance rate (3-day average) and PICS prevalence
- Follow-up
- 6 months
Methodological detailsmulticentre
- Multicentre
Primary result
As reported in the abstract
Bundle compliance rate
PICS vs non-PICS: P = 0.61 · PICS vs non-PICS: P = 0.56
Further findings
Bundle compliance rate by 6-month mortality · significantly lower in the 6-month mortality group
P = 0.031
- Bundle compliance rate by 6-month mortality — Total bundle compliance rate
- 69.8%
Mortality
- In-hospital death
- 33 (17.3%)
- Death within 6 months
- 48 (25.1%)
Correlation of bundle compliance rate with PICS prevalence, high-volume centers (subgroup)
- Strong negative correlation, r
- −0.84
- R 2
- 0.71
- p
- P = 0.035
Original publication
Evaluation of the Impact of ABCDEF Bundle Compliance Rates on Postintensive Care Syndrome: A Secondary Analysis Study*. Crit Care Med. Published 23 June 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →