Evaluation of Quality of Recovery With Quality of Recovery-15 Score After Closed-Loop Anesthesia Delivery System-Guided Propofol Versus Desflurane General Anesthesia in Patients Undergoing Transabdominal Robotic Surgery: A Randomized Controlled Study
Authors' conclusion
Automated propofol TIVA administered by CLADS is superior to desflurane inhalation GA with respect to early postoperative recovery as comprehensively assessed on the QoR-15 scoring system.
Study context
- Population
- Patients undergoing elective robotic abdominal surgery under general anesthesia (GA)
- Participants
- 120 patients
- Comparison
- Closed-loop anesthesia delivery system (CLADS)-guided propofol total intravenous anesthesia (TIVA) vs desflurane GA
- Primary endpoint
- Postoperative QoR-15 score
- Follow-up
- POD-1 and POD-2
Primary result
As reported in the abstract
CLADS
114.5
± 13
Desflurane
102.1
± 20.4
P = 0.001
Secondary outcomes
| Outcome | CLADS | Desflurane | P value |
|---|---|---|---|
| Overall QoR-15 score · POD-2Co-primary outcome | 126.0 ± 13.6 | 116.3 ± 20.3 | P = 0.011 |
QoR-15 items: feeling rested (7.5 ± 1.9 vs 6.4 ± 2.2, P = .007), good sleep (7.8 ± 1.9 vs 6.6 ± 2.7, P = .027), feeling comfortable and in control (8.1 ± 1.7 vs 6.9 ± 2.4, P = .006) · POD-1
- CLADS scored significantly higher on 3 individual QoR-15 items
QoR-15 items: feeling rested (8.1 ± 1.4 vs 7.0 ± 2.0, P = .003), return to work or usual home activities (6.0 ± 2.2 vs 4.6 ± 2.6, P = .008), comfortable and in control (8.6 ± 1.2 vs 7.7 ± 1.9, P = .004), general well-being (7.8 ± 1.6 vs 6.9 ± 2.0, P = .042), severe pain (9.0 ± 1.9 vs 8.1 ± 2.5, P = .042) · POD-2
- CLADS significantly outscored desflurane on 5 individual QoR-15 items
Original publication
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