Respiratory failure & ventilation

Executive Summary: International Clinical Practice Guidelines for Pediatric Ventilator Liberation, A Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network Document

Am J Respir Crit Care MedPublished Clinical practice guideline

Recommendations

As issued by the authors

  1. Systematic screening using an extubation readiness testing bundle, with a spontaneous breathing trial as part of the bundle (3 questions met ⩾80% agreement by Modified Convergence of Opinion on Recommendations)

  2. Most conditional, low to very low certainty of evidence

    12 recommendations from 5 systematic reviews on the methods and duration of spontaneous breathing trials, respiratory muscle strength, risk of postextubation upper airway obstruction and its prevention, postextubation noninvasive respiratory support, and sedation

Original publication

Executive Summary: International Clinical Practice Guidelines for Pediatric Ventilator Liberation, A Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network Document. Am J Respir Crit Care Med. Published 1 January 2023. doi:10.1164/rccm.202204-0795so

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