Exploring heterogeneity of treatment effect in patients with sepsis: Protocol for a scoping review
Study context
- Population
- Trials on sepsis or septic shock in which heterogeneity of treatment effect (HTE) was analysed using predictive approaches
Methodological detailsPRISMA extension for scoping reviews, Narrative summaries with descriptive statistics, Search of Medline, EMBASE, Central, Cinahl and Google Scholar, Data charted: trial characteristics, demographics, disease severity, interventions, outcomes and average treatment effect (ATEs), predictive approach, HTE results, whether HTE analysis would change an ATE-based conclusion
- PRISMA extension for scoping reviews
- Narrative summaries with descriptive statistics
- Search of Medline, EMBASE, Central, Cinahl and Google Scholar
- Data charted: trial characteristics, demographics, disease severity, interventions, outcomes and ATEs, predictive approach, HTE results, whether HTE analysis would change an ATE-based conclusion
No results yet. This paper sets out the design of a trial; its results are to come.
Original publication
Exploring heterogeneity of treatment effect in patients with sepsis: Protocol for a scoping review. Acta Anaesthesiol Scand. Published 8 July 2024. doi:10.
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