Respiratory failure & ventilation
Extracorporeal membrane oxygenation for tuberculosis-related acute respiratory distress syndrome: An international multicentre retrospective cohort study
Authors' conclusion
The use of ECMO for TB-related ARDS appears to be justifiable. Patients with miliary TB have a much better prognosis compared to those with cavitary TB on VV ECMO.
Study context
- Population
- Patients with severe tuberculosis (TB)-related acute respiratory distress syndrome (ARDS) on extracorporeal membrane oxygenation (ECMO), 20 ECMO centres in 13 countries, 2002–2022
- Participants
- 79 patients
- Exposure
- Cavitary TB vs Miliary TB
- Cavitary TBn = 61reference
- Miliary TBn = 18
- Outcome
- 90-day mortality
- Follow-up
- 90 days
Methodological detailsinternational, multicentre
- International
- Multicentre
Main finding
As reported in the abstract
90-day survival
Overall 90-day survival rate
51%
Observational data: associations, not effects.
Further findings
90-day survival, VV ECMO (subgroup)
P = 0.02
ECMO duration
- Median ECMO duration, days [10 to 34]
- 20
ICU stay
- Median ICU stay, days [24 to 65]
- 42
Safety
ECMO-related complications
- Major bleeding
- 23%
- VAP
- 41%
- Bloodstream infections
- 32%
Original publication
Extracorporeal membrane oxygenation for tuberculosis-related acute respiratory distress syndrome: An international multicentre retrospective cohort study. Crit Care. Published 9 October 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →