Pediatric anesthesia & critical care
Factors associated with immediate and early extubation in pediatric living‐donor liver transplant recipients
Main findingResult — go to the resultAdjusted odds ratio 0.52 95% CI 0.30–0.89Authors' conclusion
Our findings indicated that 39% of the pediatric living donor-liver transplantation patients tolerated early extubation and that the only associated factor was anhepatic time.
Study context
- Population
- Pediatric living-donor liver transplant recipients, January 2013 to December 2021included in the analysis
- Participants
- 79 recipients
- Exposure
- Early vs delayed extubation
- Early extubationn = 31
- Outcome
- Factors associated with early extubation (univariate and multivariate analyses)
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Adjusted odds ratio
0.52
95% CI 0.30–0.89
P = 0.018
Events by group
Early extubation
39%
31
Shorter anhepatic time
aOR 0.52 (95% CI 0.30–0.89); P = 0.018
Per 30-min increment, as printed
Observational data: associations, not effects.
Secondary outcomes
| Outcome | P value |
|---|---|
| ICU LOSShorter in the early extubation group | P = 0.001 |
Hospital LOS
- No significant differences between the groups
Safety
| Outcome | P value |
|---|---|
| Total and early medical complications; total reintubation in 30 daysDelayed extubation vs Early extubation | P = 0.002 |
| Total and early medical complications; total reintubation in 30 daysDelayed extubation vs Early extubation | .044 |
| Total and early medical complications; total reintubation in 30 daysDelayed extubation vs Early extubation | .006 |
- Total and early medical complications; total reintubation in 30 days: total medical complications significantly higher in delayed extubation
- Total and early medical complications; total reintubation in 30 days: early medical complications significantly higher in delayed extubation
- Total and early medical complications; total reintubation in 30 days: total reintubation in 30 days significantly higher in delayed extubation
Original publication
Factors associated with immediate and early extubation in pediatric living‐donor liver transplant recipients. Paediatr Anaesth. Published 5 October 2022. doi:10.
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