Paediatric anaesthesia & critical care
Rates, Outcomes and Predictors of Immediate and Early Extubation After Pediatric Liver Transplantation
Authors' conclusion
IE/EE after pediatric LT is increasingly common and has been associated with a high degree of safety and favorable outcomes. Recipient age, preoperative care setting, and intraoperative regional anesthesia are significant predictors of success.
Study context
- Population
- Patients aged ≤ 18 years undergoing isolated liver transplantation (LT), January 1, 2013–December 31, 2021, high-volume North American center
- Participants
- 245 patients
- Exposure
- Immediate intraoperative or early extubation vs delayed extubation
- Intraoperative extubation (IE)n = 33
- Early extubation (EE)n = 110
- Outcome
- Incidence, outcomes and predictors of successful IE/EE
Methodological detailssingle-centre, high-volume
- Single-centre
- High-volume
Main finding
As reported in the abstract
Incidence of IE/EE and predictors
IE
33
events
EE
110
events
- Predictive model discrimination, C-statistic
- 0.82 (95% CI 0.77-0.88)
Observational data: associations, not effects.
Further findings
- Significantly shorter intensive care unit (ICU) and hospital LOS in IE/EE vs delayed extubation (DE)
Safety
Events
| Outcome | IE | EE |
|---|---|---|
| Reintubation | 0 | 0 |
Reintubation
- No cases of reintubation
Original publication
Rates, Outcomes and Predictors of Immediate and Early Extubation After Pediatric Liver Transplantation. Paediatr Anaesth. Published 20 August 2026. doi:10.
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