Pediatric anesthesia & critical care
Anesthesia management for pediatric intestinal transplantation—a single-centre case series of eleven patients
Authors' conclusion
With careful preoperative planning, judicious fluid management, and anticipation of potential hemodynamic instability, including postreperfusion syndrome, our data show that pediatric intestinal transplantation can be performed safely, with improved long-term outcomes compared with previous reports.
Study context
- Population
- Children undergoing intestinal transplantation at a tertiary children's hospital, January 2012–August 2023
- Participants
- 11 children
- Exposure
- Isolated intestinal vs Multivisceral vs Liver and intestine
- Isolated intestinaln = five
- Multivisceraln = four
- Liver and intestinen = two
- Outcome
- Perioperative management and outcomes
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
- Gastroschisis as predominant diagnosis of intestinal failure
- 5/11, 45%
- Progressive liver disease as main indication for transplantation
- 6/11, 55%
- Postreperfusion syndrome
- 5
- Hypothermia (T < 35 °C)
- eight (73%)
- ≥1 intraoperative vasopressor/inotrope (first-line norepinephrine)
- 10
- Extubated in the operating room
- 3
- Median ICU stay of extubated patients
- three days
- 1-year patient and graft survival
- 91% (10/11)
Observational data: associations, not effects.
Original publication
Anesthesia management for pediatric intestinal transplantation—a single-centre case series of eleven patients. Can J Anaesth. Published 6 June 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →