ICU sedation, delirium & recovery

Factors of prolonged-grief-disorder symptom trajectories for ICU bereaved family surrogates

Crit CarePublished Prospective cohort study

Authors' conclusion

Membership in the PGD-symptom trajectories was associated with factors modifiable by high-quality ICU care, including anxiety symptoms at early bereavement and surrogate-perceived QODD in the ICU.

Study context

Population
ICU bereaved family surrogates
Participants
291 family surrogates
Exposure
Recovery and chronic vs resilient prolonged-grief-disorder (PGD)-symptom trajectories, by risk factor
  • Resilientn = 242reference
  • Recoveryn = 35
  • Chronicn = 14
Outcome
Factors associated with PGD-symptom trajectory membership (intrapersonal, interpersonal, bereavement-related, death-circumstance [QODD])
Methodological detailsmultinomial logistic regression
  • Multinomial logistic regression

Main finding

As reported in the abstract

Factors associated with trajectory membership
Each group vs resilientAdjusted odds ratio (95% CI)
Recoveryper increase in surrogate age
0.918(0.849–0.993)
Chronicper increase in surrogate age
1.230(1.010–1.498)
Recoverybeing married
0.186(0.047–0.729)
Recoveryhigher anxiety symptoms 1 month post loss
1.520(1.256–1.840)
Chronichigher anxiety symptoms 1 month post loss
2.022(1.444–2.831)
Chronicper increase in patient age
0.779(0.614–0.988)
Recoverypoor-to-uncertain vs high QODD class; nearly significant
4.342(0.980–19.248)

Observational data: associations, not effects.

Original publication

Factors of prolonged-grief-disorder symptom trajectories for ICU bereaved family surrogates. Crit Care. Published 11 November 2024. doi:10.1186/s13054-024-05160-2

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