Neuroanesthesia & neurocritical care
Feasibility and optimal choice of stimulation parameters for supramaximal stimulation of motor evoked potentials
Authors' conclusion
Moreover, when using supramaximal stimulation, short ISI's (i.e. 1ms or 1.5ms) can be the optimal ISI for obtaining the highest mTc-MEP amplitude.
Study context
- Population
- Consecutive patients undergoing scoliosis surgery with mTc-MEP monitoring9 excluded, 38 analysed
- Participants
- 47 patients
- Exposure
- Setting 1 vs setting 2 for supramaximal mTc-MEP stimulation
- Outcome
- Feasibility of supramaximal stimulation of mTc-MEP
Methodological detailsconsecutive patients, within-patient comparison of two stimulation settings
- Consecutive patients
- Within-patient comparison of two stimulation settings
Main finding
As reported in the abstract
Supramaximal stimulation achieved
Setting 1
38
events
Setting 2
68.42%
26 events
Observational data: associations, not effects.
Further findings
- Supramaximal stimulation with ≥ 20 V below maximum output — Setting 2
- 38.46%
Elicitability of mTc-MEPs
- In one patient, mTc-MEPs elicitable in more muscles with setting 1
mTc-MEP amplitude
- Amplitudes not significantly different
Optimal interstimulus interval (ISI) (1ms-4ms), setting 1
- Optimal ISIs differed widely
Original publication
Feasibility and optimal choice of stimulation parameters for supramaximal stimulation of motor evoked potentials. J Clin Monit Comput. Published 13 January 2023. doi:10.
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