Pain medicine

Feasibility of virtual reality‐delivered pain psychology therapy for cancer‐related neuropathic pain: a pilot randomised controlled trial

AnaesthesiaPublished Pilot randomised controlled trial

Authors' conclusion

This newly created virtual reality-delivered pain therapy software programme was shown to be feasible and acceptable to cancer patients with neuropathic pain.

Study context

Population
Cancer patients with neuropathic painof 87 eligible
Participants
39 patients
Comparison
VR pain therapy software programme vs viewing VR videos
  • Interventionn = 20
  • Controln = 19reference
Primary endpoint
Feasibility, acceptability, recruitment rates and risk of cybersickness
Methodological detailsfeasibility study
  • Feasibility study

Primary result

As reported in the abstract

Feasibility, acceptability, recruitment and cybersickness

Recruited of eligible

47%

Withdrew before 3-month follow-up (all control)

4

Pre-existing dizziness associated with cybersickness (Spearman ρ, p = 0.02)

0.37

Pre-existing nausea associated with cybersickness (Spearman ρ, p < 0.001)

0.81

Further findings

OutcomeInterventionControl
Change in oral morphine equivalent daily dose opioid consumption · 1 and 3 monthsTrends in the intervention group towards reductions−8 mg and −4 mg mg0 mg and +15 mg mg
Change in modified Brief Pain Inventory pain severity · 1 and 3 monthsTrends in the intervention group towards reductions−0.4, −0.8+0.4, −0.3
Change in pain interference · 1 and 3 monthsTrends in the intervention group towards reductions−0.9, −1.8−0.2, −0.3
Change in global quality of life (EORTC QLQ-C30 subscale) · 1 and 3 months−5, −8+3, +4

Change in global quality of life (EORTC QLQ-C30 subscale) · 1 and 3 months

Not significantly changed between groups

Original publication

Feasibility of virtual reality‐delivered pain psychology therapy for cancer‐related neuropathic pain: a pilot randomised controlled trial. Anaesthesia. Published 2 February 2023. doi:10.1111/anae.15971

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