Fever following extracorporeal membrane oxygenation decannulation: Infection, thrombosis or just physiology?
Authors' conclusion
Post-decannulation fever was common, and was mainly due to infections or thrombosis.
Study context
- Population
- Adult extracorporeal membrane oxygenation (ECMO) patients successfully weaned from ECMO, January 2021–December 2022successfully weaned from ECMO
- Participants
- 123 participants
- Exposure
- Post-decannulation fever by cause
- Outcome
- Incidence of post-decannulation fever
- Follow-up
- Up to 5 days after decannulation
Main finding
As reported in the abstract
Post-decannulation fever
Post-decannulation fever
54 patients
44 %
Associated with infection
39 patients
72 %
Associated with thrombosis
6 patients
11 %
No cause identified
9
17 %
Observational data: associations, not effects.
Further findings
Risk factors for infection
- Prolonged ECMO duration, extended ICU LOS, diabetes and vascular comorbidities significantly associated with higher risk of infection
Pro-inflammatory cytokine profiles, febrile vs afebrile (20 patients)
- Did not differ between febrile and afebrile patients
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Fever following extracorporeal membrane oxygenation decannulation: Infection, thrombosis or just physiology? J Crit Care. Published 11 November 2024. doi:10. 1016/ j. jcrc. 2024. 154945
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