Hemodynamics, fluids & transfusion
Fluid Intake in Critically Ill Patients: The “Save Useless Fluids For Intensive Resuscitation” Multicenter Prospective Cohort Study*
Authors' conclusion
Fluids indisputably required for body fluid homeostasis represent the minority of fluid intake during the 24 hours after ICU admission. Center effect is the strongest factor associated with the volume of fluids.
Study context
- Population
- Patients requiring vasopressors and/or invasive mechanical ventilation in 30 ICUs in France and one in Spainmulticentre cohort
- Participants
- 296 patients
- Outcome
- Heterogeneity of fluid intake at the initial phase of resuscitation (all fluids by vascular or enteral lines)
- Follow-up
- 24 hours following admission
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
Fluid intake over 24 h after admission · 24 hours
- Total volume of fluids, median (IQR 2441-4955 mL)
- 3546 mL
- Share of total from fluids indisputably required for body fluid homeostasis
- 36%
- Share of total volume: saline
- 43%
- Share of total volume: glucose-containing high chloride crystalloids
- 27%
- Share of total volume: balanced crystalloids
- 16%
Observational data: associations, not effects.
Further findings
| Outcome | Tertile 2 | Tertile 3 |
|---|---|---|
| Difference between volume predicted by patient characteristics and volume given, by center tertile of fluid intake (vs first tertile)Compared with the first tertile | +1.2 ± 2.0 L | +3.0 ± 2.8 L |
Original publication
Fluid Intake in Critically Ill Patients: The “Save Useless Fluids For Intensive Resuscitation” Multicenter Prospective Cohort Study*. Crit Care Med. Published 1 November 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →