ICU sedation, delirium & recovery
Frailty and Long-Term Survival in Patients With Critical Illness After Nonhome Discharge: A Retrospective Cohort Study
Authors' conclusion
Frailty was independently associated with shorter time to death following a nonhome discharge after an ICU admission.
Study context
- Population
- Medical patients (≥ 16 yr) admitted to Australian and New Zealand ICUs with documented Clinical Frailty Scale (CFS) and nonhome discharge, January 1, 2018, to March 31, 2022
- Participants
- 57,652 patients
- Exposure
- Frailty vs no frailty
- Frailn = 17,383
- Outcome
- Survival time
- Follow-up
- Up to 4 years
Methodological detailsmulticentre, Cox proportional hazards regression with robust sandwich variance estimators
- Multicentre
- Cox proportional hazards regression with robust sandwich variance estimators
Main finding
Survival time up to 4 years
AHR for death
1.50
95% CI 1.43–1.57
By group
Frail vs Not frail
aHR for death 1.50 (95% CI 1.43–1.57)
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | aHR for death (95% CI) | |
|---|---|---|
| Death by age (subgroup)Frail vs Not frail · age <65 yr | 1.73 (1.59–1.88) | |
| Death by age (subgroup)Frail vs Not frail · age 65-80 yr | 1.47 (1.38–1.57) | |
| Death by age (subgroup)Frail vs Not frail · age >80 yr | 1.35 (1.26–1.45) | |
| Death by nonhome discharge location (subgroup)Frail vs Not frail · discharged to rehabilitation | 1.52 (1.39–1.65) | |
| Death by nonhome discharge location (subgroup)Frail vs Not frail · discharged to acute hospitals | 1.56 (1.48–1.65) | |
| Death by nonhome discharge location (subgroup)Frail vs Not frail · discharged to RACF | 0.94 (0.83–1.06) | |
| 0.512AHR for death (log scale) |
Original publication
Frailty and Long-Term Survival in Patients With Critical Illness After Nonhome Discharge: A Retrospective Cohort Study. Crit Care Med. Published 29 April 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →