Cardiac arrest & resuscitation
The impact of frailty on survival times up to one year among patients admitted to intensive care units (ICU) with in-hospital cardiac arrest
Authors' conclusion
In this retrospective multicentre study, frailty was associated with poorer one-year survival in patients admitted to Australian ICUs following an IHCA.
Study context
- Population
- Critically ill adults (age ≥ 16 years) admitted to Australian ICUs 2018–2022 with in-hospital cardiac arrest (IHCA) within 24 h before ICU admission and documented Clinical Frail Scale
- Participants
- 3,769 adults
- Exposure
- Frail vs non-frail
- Frailn = 1,160
- Outcome
- Median survival up to one year following ICU admission
- Follow-up
- Up to one year
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
Median survival
P < 0.001
Observational data: associations, not effects.
Further findings
| Outcome | aHR for death (95% CI) | |
|---|---|---|
| Death up to one year, per unit increment in CFS | 1.22 (1.19–1.26) | |
| 0.512AHR for death (log scale) |
| Outcome | Frail | Non-frail | P value |
|---|---|---|---|
| One-year mortality | 64.8% (95% CI 61.9–67.5) | 36.4% (95% CI 34.5–38.3) | P < 0.001 |
- Death up to one year, per unit increment in Clinical Frail Scale (CFS): 22% worse survival; adjusted for age, sex, comorbidities, sequential organ failure assessment (SOFA) score, hospital type
Survival among hospital survivors
- Survival trend similar among patients who survived the hospitalization
Original publication
The impact of frailty on survival times up to one year among patients admitted to ICU with in-hospital cardiac arrest. J Crit Care. Published 11 June 2024. doi:10.
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