Perioperative medicine & outcomes
Frailty and long-term survival of non-cancer patients admitted to intensive care after surgery: a retrospective multicentre cohort study
Authors' conclusion
In this multicentre study, frailty was associated with shorter time to death amongst postoperative ICU patients without cancer. The association was concordant across all subgroups.
Study context
- Population
- Adults aged ≥16 yr without cancer admitted to 175 Australian ICUs after surgery, January 2018–March 2022
- Participants
- 216,922 adults
- Exposure
- Frail vs not frail
- Frailtyn = 30,860
- Outcome
- Survival time after ICU admission
- Follow-up
- Up to 4 yr
Methodological detailsmulticentre, registry linkage, mixed-effects Cox regression
- Multicentre
- Registry linkage
- Mixed-effects Cox regression
Main finding
Overall survival time · up to 4 yr after ICU admission
HR for death
2.33
95% CI 2.26–2.40
By group
Frail vs Not frail
HR for death 2.33 (95% CI 2.26–2.40)
As reported in the abstract
Observational data: associations, not effects.
Further findings
- Association consistent across sensitivity analyses and subgroups
- Association more pronounced in patients aged <65 yr, elective surgery, and without treatment limitations
Original publication
Frailty and long-term survival of non-cancer patients admitted to intensive care after surgery: a retrospective multicentre cohort study. Br J Anaesth. Published 23 April 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →