Perioperative medicine & outcomes

Frailty as an independent risk factor for prolonged postoperative length of stay: A retrospective analysis of 2015–2019 ACS NSQIP data

J Clin AnesthPublished Retrospective cohort study

Authors' conclusion

Frailty is an independent risk factor for prolonged postoperative LOS among older surgical patients, even after adjustment for patient and procedure covariates.

Study context

Population
Patients aged 65+ undergoing inpatient surgery including emergency procedures, ACS NSQIP 2015–201929.0 % frail
Participants
1,254,809 patients
Exposure
Frail vs non-frail
Outcome
Median postoperative LOS
Methodological detailsACS NSQIP registry data 2015–2019, adjusted analysis, subgroup analysis
  • ACS NSQIP registry data 2015–2019
  • Adjusted analysis
  • Subgroup analysis

Main finding

As reported in the abstract

Increase in median LOS, days (95 % CI)
mFI-5 score of 5 vs mFI-5 score of 0adjusted analysis
3(2.79–3.22)
mFI-5 scores of 4 vs mFI-5 scores of 0unadjusted analysis
3.5(3.36–3.64)
mFI-5 scores of 5 vs mFI-5 scores of 0unadjusted analysis
4.64(3.96–5.32)

Observational data: associations, not effects.

Further findings

Characteristics, frail vs non-frail

Black

Hispanic

ASA class IV/V

Malnourished

Vascular surgery

Increase in median length of stay (LOS) per one-point increase in mFI-5 (subgroups)

Emergency surgery
0.5 days, 95 % CI 0.48-0.52
Lower extremity bypass surgery
0.53 days, 95 % CI 0.47-0.59
  • Strongest associations

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Frailty as an independent risk factor for prolonged postoperative length of stay: A retrospective analysis of 2015–2019 ACS NSQIP data. J Clin Anesth. Published 20 December 2024. doi:10.1016/j.jclinane.2024.111730

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