Pediatric anesthesia & critical care
Functional near‐infrared spectroscopy guided mapping of frontal cortex, a novel modality for assessing emergence delirium in children: A prospective observational study
Authors' conclusion
There is significant difference in the change in oxyhemoglobin concentration during induction, maintenance, and emergence in specific frontal brain regions between children with and without emergence delirium.
Study context
- Population
- ASA I and II children aged 2–5 years undergoing ocular examination under anesthesia (O2, N2O, sevoflurane)
- Participants
- 145 participants
- Exposure
- ED+ vs ED-
- ED+n = 59
- Outcome
- Correlation of emergence delirium with frontal cortex changes on fNIRS
Main finding
As reported in the abstract
Frontal cortex activity (fNIRS), ED+ vs ED-
- Induction: activation left superior frontal cortex
- t 2.26E+00; P = 0.02
- Induction: activation right middle frontal cortex
- t 2.27E+00; P = 0.02
- Maintenance: depression left middle frontal
- t −2.22E+00; P = 0.02
- Maintenance: depression left superior frontal and bilateral medial
- t −3.01E+00; P = 0.003
- Maintenance: depression right superior frontal and bilateral medial
- t −2.44E+00; P = 0.015
- Maintenance: depression bilateral medial and superior
- t −3.03E+00; P = 0.003
- Maintenance: depression right middle frontal cortex
- t −2.90E+00; P = 0.004
- Emergence: activation left superior frontal cortex
- t 2.01E+00; P = 0.0047
Observational data: associations, not effects.
Further findings
Incidence of emergence delirium
- Children with emergence delirium
- 59 (40.7%)
Original publication
Functional near‐infrared spectroscopy guided mapping of frontal cortex, a novel modality for assessing emergence delirium in children: A prospective observational study. Paediatr Anaesth. Published 14 June 2023. doi:10.
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