Neuroanesthesia & neurocritical care
Functional Outcomes Associated With Blood Pressure Decrease After Endovascular Thrombectomy
Authors' conclusion
In this cohort study of patients with successful endovascular thrombectomy after stroke, MIBD within 24 hours after successful recanalization was associated with poor outcomes at 3 months.
Study context
- Population
- Patients with successful recanalization after endovascular thrombectomy and elevated blood pressure (BP) within 2 hours, 19 stroke centers in South Korea
- Participants
- 302 patients · 19 stroke centers
- Comparison
- Medication-induced or spontaneous BP decrease vs no BP decrease after successful endovascular thrombectomy
- Medication-induced BP decrease (MIBD)n = 47
- Spontaneous BP decrease (SpBD)n = 39
- No BP decrease (NoBD)n = 216reference
- Primary endpoint
- Functional independence (modified Rankin scale score 0 to 2)
- Follow-up
- 3 months
Methodological detailscohort study, multicentre
- Cohort study
- Multicentre
Primary result
As reported in the abstract
Functional independence (mRS 0-2)
Each group vs NoBDAdjusted odds ratio (95% CI)
MIBD
0.45(0.20–0.98)
SpBD
1.41(0.58–3.49)
Further findings
| Outcome | aOR (95% CI) | |
|---|---|---|
| Mortality due to index stroke · within 3 monthsMIBD vs NoBD | 5.15 (1.42–19.4) | |
| 0.050.21520Adjusted odds ratio (log scale) |
Safety
| Outcome | aOR (95% CI) | |
|---|---|---|
| Symptomatic intracerebral hemorrhage · within 36 hoursMIBD vs NoBD · not significantly different among the groups | 1.89 (0.54–5.88) | |
| Symptomatic intracerebral hemorrhage · within 36 hoursSpBD vs NoBD · not significantly different among the groups | 2.75 (0.76–9.46) | |
| 0.10.31310Adjusted odds ratio (log scale) |
Original publication
Functional Outcomes Associated With Blood Pressure Decrease After Endovascular Thrombectomy. JAMA Netw Open. Published 1 April 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →